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Search Results for " rock inhibitor "

20

Compounds

Cat No. Product Name Synonyms Targets
T12746 ROCK inhibitor-2 ROCK
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
T4095 ZINC00881524 ROCK inhibitor ROCK
ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
T6867 Belumosudil KD025,Rezurock,ROCK inhibitor,SLx-2119 ROCK
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
T12747 ROCK2-IN-2 ROCK
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
TQ0110 ROCK-IN-2 TC-S 7001,Azaindole 1 ROCK
ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
T2011 RKI1313 RKI 1313,RKI-1313 ROCK
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion.
T2155 Thiazovivin ROCK
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
T1870 Y-27632 ROCK , Apoptosis
Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
TQ0187 SR-3677 ROCK , Autophagy
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
T24722 ROCK-IN-32 ROCK-inhibitor-32,ROCK inhibitor 32
ROCK-IN-32 is an effective Rho-kinase inhibitor.
TQ0183 Narciclasine Lycoricidinol ROCK
Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.
T24725 ROCK-IN-D3 ROCK inhibitor D3,ROCK-inhibitor-D3
ROCK-IN-D3 is an effective and selective inhibitor of ROCK.
T7391 SAR407899 ROCK , Rho
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
T15798 LX7101 ROCK , LIM Kinase , PKA
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
T7301 BDP5290 ROCK
BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)
T24723 ROCK-IN-D1 ROCK inhibitor D1,ROCK IN D1,ROCK-inhibitor-D1
ROCK-IN-D1 is an effective and selective inhibitor of ROCK.
T24724 ROCK-IN-D2 ROCK inhibitor D2,ROCK IN D2,ROCK-inhibitor-D2
ROCK-IN-D2 is an effective and selective inhibitor of ROCK.
T3513 GSK180736A GSK180736 ROCK , GRK , PKA
GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), but highly effective against ROCK1 (IC50: 100 nM).
T1898 RKI-1447 RKI1447 ROCK
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.
T14960 Chroman 1 ROCK
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM).
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